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Diltiazem 2% Ointment
Available with Lidocaine and in Gel form

Compounding Options for Treatment of Anal Fissures

An anal fissure is a small tear in the tissue that lines the anus. This may occur for a number of reasons including but not limited to passing hard or large stools, chronic diarrhea, or a complication of Crohn’s disease1. Anal fissures can cause a cycle of inflammation, pain, and spasm.

To help aid in the treatment of this condition we offer the following compounded medications: diltiazem, nifedipine, and nitroglycerin ointments, creams, or gels2.

Diltiazem and nifedipine belong to a class of medications called calcium channel blockers and help to reduce the pressure at the site of the fissure to improve healing while nitroglycerin dilates blood vessels and increases blood flow to promote healing2.

For more information on treatment options, or questions about other compounded medications offered please contact our pharmacy.

1. “Anal Fissure.” Mayo Clinic. 18 Aug 2017.
2. Wick, Jeannette Y. “Anal Fissures” A Real Pain.” Pharmacy Times, 11 July 2014.

In this study, 59 out of 67 patients treated with diltiazem 2% ointment healed from their anal fissures.